Good afternoon. I am Ronnie Morris, CEO of Champions Oncology. Joining me today is David Miller, our Chief Financial Officer. Thank you for joining us for our quarterly earnings call.

Before I begin, I will remind you that we'll be making forward-looking statements during today's call and that actual results could differ materially from what is described in those statements. Additional information on factors that could cause results to differ is available in our Forms 10-Q and Form 10-K. A reconciliation of non-GAAP financial measures that may be discussed during the call to GAAP financial measures is available in the earnings release.

Overall, we had another good quarter with solid growth in our services business, as well as progress in our software and drug discovery efforts. Oncology Research Services business had a record revenues, while our bookings remained robust. We both continue to expand our service offerings and expand our customer base, paving the way for continued growth.

We continue to be encouraged by Lumin, our new software platform that was rolled out a little more than a year ago. We have been licensing this platform to our customers using a SaaS model, and our Lumin customer base now stands in excess of 150 users. While our ultimate goal is to build a significant user base, our efforts over this past year have primarily focused on further developing the platform such as adding datasets, improving the user interface, and integrating customers' feedback into our software. Our goal is to create an indispensable tool, which will lead to a broader user base, and result in a significant recurring revenue stream in the coming years.

In conjunction with our Lumin software platform, we have launched Lumin Acuity and Lumin Workspaces. In Lumin Acuity, we provide consulting and support services to help customers answer their focused bioinformatic questions. It is often used by customers who may not have the internal resources to perform this research on their own. Lumin Workspaces is a paid-to-play model that allows users to custom code, interrogate and analyze Champions' comprehensive bioinformatic datasets. In all, we have created a multifaceted data analytics platform centered around Lumin. We are excited about the potential impact of our data analytics and software platform on our long-term growth. We are actively keying in on such metrics as the customer usage, satisfaction, and renewal rates. Over the coming quarters, we will disclose more user data as it becomes relevant to our story.

With regards to our drug development effort, we continue to make good progress. To date, we have validated more than six targets and we are now advancing those targets through the development pipeline. As we have mentioned previously, we will continue to advance each of these target either ourselves or in partnership with another entity. We will continue to explore the various opportunities to advance each target on the discovery pipeline, evaluating each to determine the most strategic and advantageous path, assessing whether we want to partner, license or internally develop each validated target. Most importantly, we believe we have a platform to discover multiple targets moving forward.

In summary, during the second quarter, our research services business continued to expand, which led to strong financial results, while we simultaneously continued to capture more value from the proprietary data that we create. Our innovative SaaS business continues to grow, and we are advancing our therapeutic targets through the pipeline.

Now, let me turn the call over to David Miller, for a more detailed review of the financial results.

David Miller - Chief Financial Officer

Thanks, Ronnie. Our full results on Form 10-Q will be filed with the SEC later today.

Our second quarter financial results were strong, with record revenue of $11.8 million, compared to $10.1 million in the year ago period, an increase of $1.7 million or 17%. We generated operating income of $263,000. And excluding stock-based compensation and depreciation, we recognized operating income of approximately $750,000, compared to $400,000 in the year-ago period.

Focusing as we do on results excluding non-cash expenses such as stock comp and depreciation, our second quarter gross margin was 53%, compared to 45% for the same period last year. Total cost of sales was $5.5 million, compared to $5.6 million in our second quarter last year. As we discussed on several prior calls, our quarterly gross margins were pressured because we outsourced some lab work to accelerate revenue growth. By minimizing our reliance on outsourcing, we have reduced our total cost of sales even with increases in compensation, lab supplies, and rent, resulting from the increase in study volume and our recent lab expansion.

Over the last few years, we've continued to invest in our business to adequately support our anticipated growth. As our revenue increases and with much of the investment cost already incurred, we are realizing the leverage and anticipate an improvement in gross margin. It's also worth noting the gross margin improvement has mainly been from our core business. As higher margin products contribute more meaningfully to total revenue, there is room for additional upward trend in margin over the longer term.

R&D expense was approximately $2.3 million, compared to $1.6 million in the year-ago period, an increase of $700,000 or 39%. Those $2.3 million and overall increase is in line with guidance provided, as we indicated we will be ramping up our R&D investment adding data to our tumor bank and investing in our therapeutic target discovery platform. We expect another increase in R&D expense during the second half of the year. However, we anticipate our revenue growth should offset the additional R&D spend and our operating results will be at least be marginally positive. We reiterate that we will increase our R&D investment and sacrifice short term operating income for greater long-term growth and profitability.

Sales and marketing expense was $1.6 million, compared to $1.3 million in the year-ago period, an increase of $300,000 or 22%. The increase in sales and marketing was mainly due to compensation-related expenses resulting from the expansion of our sales team. Our G&A expense was at $1.6 million for the quarter, compared to $1.2 million a year ago, a 36% increase. The increase was primarily due to an increase in compensation expense and IT expense, as we invest in upgrading our IT infrastructure to support Company growth.

In total, our cash-based expenses were $11 million for the second quarter of fiscal 2022, compared to $9.7 million in the same period last year, an increase of approximately $1.3 million or 14% with the increase is primarily stemming from investment for future growth.

Now turning to cash. At the end of the quarter, we had $4.8 million of cash on the balance sheet, an increase of $800,000 from our prior quarter. For the quarter, net cash generating from operating activities was approximately $1.2 million due to improving cash-based operating results. Cash used in investing activities of $500,000 was primarily due to continued investment in our software platform, along the fixed asset purchases for our laboratories.

In summary, we had a strong financial quarter, hitting a new revenue record of $11.8 million. We generated operating income on both a GAAP and non-GAAP basis. And with the underlying strength in our research service business, we're positioned for continued revenue growth, while we expand our Lumin platform and advance our target discovery program. We are excited about the Company's progression, and look forward to our next update call in mid-March.

We would now like to open the call for your questions.

Question & Answers

Operator

Ladies and gentlemen, the floor is now open for questions. [Operator Instructions] Your first question is coming from Matt Hewitt with the Craig-Hallum. Your line is live.

Matt Hewitt - Craig-Hallum - Analyst

Good afternoon, gentlemen, and thank you for taking the questions. Maybe to kick things off, just a couple of items on the Lumin. Obviously, a nice jump in the number of users here this past quarter, up to 150. I'm just curious what the feedback is from those customers that have been on-board for maybe the past year? And what's driving some of the new adoption?

Ronnie Morris - President & Chief Executive Officer

Thanks. Thanks, Matt. So I think the feedback continues to be strong. People are getting used to using Lumin. I think a lot of the new users are haven't really used it enough to really understand what their adoption is. I think what we've learned is that we have to support people. We have to help them become higher user - more and more of a user. This is a new technology. This is a new software. And what we've learned through the first year is that, we need to support them more. We need to help them understand how to become a better user on the platform. So overall, as we support people, as people use Lumin more, I think that what we've gotten back is a very positive response. I would still put us in the category of the early learning. We continue to grow the user base. We continue to grow the functionality. We think the platform is getting stronger, but we're still kind of in that early stages where we're getting a lot of feedback, where we are working with the users, and we're trying to get them to be using it more and more.

Matt Hewitt - Craig-Hallum - Analyst

Got it. And then it sounds like you've added a new sales team, specifically geared towards that Lumin platform. How many members are on that team? Maybe what was their prior experience before joining Champions? And is some of their role going to be on the support side, or are they purely out finding new customers?

Ronnie Morris - President & Chief Executive Officer

Yeah, I would say it's a mixture. We have four members of the Lumin team right now that do a combination of support and sales. I would say one of the changes we've made as of late, is really getting our whole sales force more in tune with Lumin, so that they can also be out there more talking to our customers as well and becoming more proficient within Lumin, so that they can try to bring some of our customers along and bring it to our internal sales group. So, at this point, I think a lot of it is both sales, but also support in terms of getting users up to speed, in terms of support for the software itself from a technical perspective. We have a whole team that supports that outside of this team.

Matt Hewitt - Craig-Hallum - Analyst

Got it. Okay. Maybe shifting gears a little bit. I've got two questions and then I'll hop back in the queue. First up, maybe you could update us on the flow cytometry pipeline, how that's progressing? And then I guess the last question would be regarding the European lab, that you - that is officially open as of - or opened during the quarter. If you could give us an update on how those discussions are going, and whether or not you started to generate revenues out of that facility? Thank you.

Ronnie Morris - President & Chief Executive Officer

Yeah. So in terms of the - your both questions kind of go together. We opened up the European site so we can be - so we can better be in a position to do more of the larger flow cytometry, and also I would say, the biomarker in general, studies, the clinical studies. The lab, just open. We opened it a couple of months ago, but it just open to be able to start doing some work and some validations. So we really haven't seen any shift in that respect because we're literally just being able to validate some of our assays there. So I expect over the next quarter or two, we should see a real movement in whether we have the ability to win some of these larger studies.

In terms of the biomarker business, in general, it's something that we're still excited about. I think we've made great strides operationally. I think we've also done well, bring in some of the business. Probably, honestly, not as robust as I expected. I think I've mentioned that before in this call, not what we expected. I still believe we will get there, but it certainly hasn't taken the trajectory that we thought it would. I still would say that, as I look to Champions, two years from now, I still see as a large percent - a significant contributor to our growth, but it really hasn't played out that way as of yet. A lot of the other parts of the business have grown at a faster pace. I do like the signs that we're seeing in terms of just the work that we're doing, the quality of the conversations we're having with our customers, the team that we've built. And I think it's a matter of time, certainly, taking a bit longer than I expected though.

Matt Hewitt - Craig-Hallum - Analyst

Understood. Great. Thank you very much for taking the questions.

Ronnie Morris - President & Chief Executive Officer

Welcome, Matt.

Operator

Your next question is coming from Scott Henry. Your line is live.

Scott Henry - ROTH Capital Partners - Analyst

Thank you, and good afternoon. Just a couple of questions. First, another strong sequential gain from first quarter to second quarter of fiscal '22. Would you care to make any comments on the second half of the year? I believe we're looking - thinking about sequential gains in the next few quarters as well, perhaps even larger gains. Just any thoughts you have on that, would be great.

Ronnie Morris - President & Chief Executive Officer

Sure. I'll take that quickly. So, I do anticipate that we'll have sequential gain in the second half of the year over the first half of the year. But there is no need to change any of the guidance that's currently been provided. We will be towards the higher end of the guidance, but there is no need to change it at this point.

Scott Henry - ROTH Capital Partners - Analyst

Okay, perfect. Thank you. And then the gross margin of 52% in 2Q, do you expect - I mean that was a pretty good number. It was a pretty good number at first quarter as well. Can we expect those levels to stay that high throughout the second half of the year?

Ronnie Morris - President & Chief Executive Officer

I do anticipate that those levels are - [Indecipherable] we should be near. It could be slightly fluctuations. But I certainly see an overall steadying of the margins that are 50% level and with an upward trend over the longer term.

Scott Henry - ROTH Capital Partners - Analyst

Okay, great. And then one more model question. $2.3 million - I think R&D was $2.3 million in 2Q.

David Miller - Chief Financial Officer

Correct.

Scott Henry - ROTH Capital Partners - Analyst

I believe you said it's going to step up in the second half of the year. What size, magnitude are we talking about? Couple of hundred thousand dollars per quarter here, or larger than that?

David Miller - Chief Financial Officer

Potentially, slightly larger than that. The exact timing of when we're going to have the ramp up is difficult to predict. But I would anticipate - we are planning on bumping that number up by $700,000 over the next, each quarter.

Scott Henry - ROTH Capital Partners - Analyst

Okay. But it sounds like that may be more pronounced in the fourth quarter than the third quarter. Did I hear that correct?

David Miller - Chief Financial Officer

It's really a - it could be a matter of timing with some of the planned expense. The - exactly whether it's could be Q3 or Q4, it's hard to tell right now.

Scott Henry - ROTH Capital Partners - Analyst

Okay, great. And then the final question. You mentioned the six targets in the proprietary pipeline. How should we think of the timeline to either partner those programs, or reach an inflection point? I mean are we thinking a year out, or are we thinking two years out? Just trying to get a sense of when we may see some catalysts on that front?

Ronnie Morris - President & Chief Executive Officer

Yeah. I think it's in between those two numbers you put out there, Scott. I think it's between a year and two years that we'll be - we'll be at the point - we'll either be in an IND-enabling stage, or we'll be at a point where we out-license it to partner. So I think that that's a reasonable kind of goalpost.

Scott Henry - ROTH Capital Partners - Analyst

Okay, great. Thank you for taking the questions.

Ronnie Morris - President & Chief Executive Officer

You're welcome. Sure.

Operator

We have no further questions from the lines at this time. I would like to turn the floor back to Dr. Ronnie Morris for closing remarks.

Ronnie Morris - President & Chief Executive Officer

Thank you. And thank you everybody for joining us for our quarterly earnings call. We are certainly excited about the direction we're taking with the expansive services business, as well as our two new efforts, which include the SaaS platform, our software platform as well as our drug development. This is incredibly exciting time for Champions Oncology. We feel we're on the right path, and we're at an inflection point. So we look forward to continuing our updates over the next couple of quarters with everybody on this call. Thank you and have a good evening.

Operator

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CHAMPIONS ONCOLOGY INC

Q2 2022

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