Gufic Biosciences announced that CRISIL Ratings Limited has upgraded its long-term and short-term ratings on the companys bank facilities to CRISIL A- with a stable outlook from CRISIL BBB+ and CRISIL A2+ from CRISIL A2, respectively. The total bank loan facilities rated now stand at Rs. 425 Crore (Enhanced from Rs. 275 Crore).