Novo Nordisk announced successful Phase 3a trial results on January 8, 2024, for once-weekly IcoSema, showing comparable efficacy in lowering blood sugar and significant weight loss compared to daily insulin treatments. The trial involved 679 participants with type 2 diabetes and demonstrated a reduction in HbA1c by -1.47% for IcoSema versus -1.40% for daily insulin, achieving a significant weight change of -6.7 kg.