On December 16, 2025, Nektar Therapeutics announced the topline results from its Phase 2b REZOLVE-AA clinical trial for alopecia areata, showing a mean SALT score reduction of 28.2% for the 24 µg/kg dosage and 30.3% for the 18 µg/kg dosage compared to 11.2% for placebo, with some results reaching statistical significance after excluding specific eligibility violations.