On June 9, 2025, NewAmsterdam Pharma Company N.V. announced positive topline results from its Phase 3 BROADWAY clinical trial for Alzheimer’s Disease, showing significant reductions in biomarkers linked to the disease, with a study of 1,727 patients, including 367 ApoE4 carriers. The results showed a statistically significant lower change in the p-tau217 biomarker compared to placebo.